Chesterfield's Football League survival hopes were hanging by a thread after rivals Mansfield revived their play-off aspirations with a 1-0 win at the Proact St
Colchester will hand late fitness tests to Brennan Dickenson and Tom Lapslie before selecting their team to host League Two leaders Accrington.
Notts County manager Kevin Nolan is expected to make changes against Coventry as he attempts to get his side's promotion challenge back on track.
Cheltenham expect to be without Carl Winchester as they look to get back to winning ways against struggling Morecambe.
Barnet boss Martin Allen could again look to freshen up his relegation-threatened side for the Sky Bet League Two visit of fellow strugglers Forest Green Rovers
Sam Hornby looks likely to start in goal for Port Vale on Saturday when they host Crawley.
Mansfield hope to have top scorer Danny Rose available to play some part against Crewe.
Grimsby look set to be without forwards Simeon Jackson and Mallik Wilks for the basement battle with Chesterfield.